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This article explores the history and global impact of the HIV/AIDS epidemic, from its discovery in 1981 to advancements in treatment and prevention, such as antiretroviral therapy (ART). It highlights progress, challenges, and the ongoing need for equitable healthcare access and stigma reduction.

What we did?

We gathered reliable data from sources like UNAIDS, WHO, and IHME to analyze the origin and evolution of AIDS, focusing on global goals and prevention strategies. A clear layout was designed to present key facts and figures, guiding readers from the history of AIDS to modern precautions. Simple and impactful illustrations, along with real-world examples and case studies, were used to ensure the message is engaging, accessible, and effectively spread to society.

Today, the HIV/AIDS story is one of progress and opportunity. Antiretroviral therapy (ART) was introduced in the mid-1990s and has become widely available in recent years, allowing people living with HIV to enjoy long, healthy lives. ART works by reducing viral load in the bloodstream to undetectable levels, hence stopping transmission. This notion, represented in the potent U=U (Undetectable = Untransmittable) statement, has formed the foundation of global HIV prevention efforts.

By 2022, roughly 28 million people globally would be receiving ART, demonstrating the collaborative efforts of governments, organizations, and healthcare systems. As a result, annual AIDS-related mortality have dropped by 69% since their peak, with considerable reductions among women and girls, who nevertheless make up 53% of individuals living with HIV. Despite these advancements, difficulties remain. Stigma and unequal access to healthcare remain important impediments, particularly in Eastern Europe, Central Asia, Africa, and the Middle East. In 2023, 630,000 individuals died from AIDS-related illnesses, highlighting the urgent need for comprehensive care and mitigation.

UNAIDS
Strategic priority 1:
Ensuring that everyone has access to HIV services, including key populations at higher risk of HIV, such as sex workers, men who have sex with men, and people who inject drugs.
Strategic priority 2:
Tackling stigma, discrimination, and gender inequality that drive HIV vulnerability, particularly in marginalized populations. Advocating for legal reforms to protect human rights, reduce stigma, and enable equitable access to HIV services.
Strategic priority 3:
Building resilient health systems that can address not only HIV but also other health needs, such as TB and maternal health. Securing sustainable financing for HIV programs, ensuring that funding reaches the most vulnerable and ensures progress towards ending AIDS.

Since its discovery in 1981, the HIV/AIDS epidemic has impacted the history of global health, emphasizing humanity's deficiencies while also demonstrating resilience and ingenuity. What began as a strange ailment mostly affecting young males in the United States quickly turned into a global crisis. In 1983, scientists discovered that the human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS), a condition that annihilates the immune system and renders the body incapable to fight infections.

By the 1990s, AIDS had become one of the most dreadful health catastrophes in modern history, killing millions of people each year. The epidemic's peak in 2004 witnessed almost 2 million deaths in a single year, with marginalized communities—gay males, sex workers, and sub-Saharan African populations—bearing the brunt of the disease's impact. 

During the early decades, the situation was aggravated by global inaction, as well as stigma and prejudice. Treatments were severely limited, and the virus's mysterious nature fuelled fear and misinformation. Despite the despondency, grassroots movements and advocates formed to demand equity, education, and action. These activities paved the way for future advances in HIV/AIDS treatment and prevention.

Strategies and Treatments

Kick and Kill
Scientific discoveries are also influencing the course of disease. The 'kick and kill strategy, developed at UCLA, represents novel approaches of eliminating HIV reservoirs in the body. Early animal trials have demonstrated the potential for total viral eradication, providing a glimpse of future without HIV.

Today, the HIV/AIDS story is one of progress and opportunity. Antiretroviral therapy (ART) was introduced in the mid-1990s and has become widely available in recent years, allowing people living with HIV to enjoy long, healthy lives. ART works by reducing viral load in the bloodstream to undetectable levels, hence stopping transmission. This notion, represented in the potent U=U (Undetectable = Untransmittable) statement, has formed the foundation of global HIV prevention efforts.

By 2022, roughly 28 million people globally would be receiving ART, demonstrating the collaborative efforts of governments, organizations, and healthcare systems. As a result, annual AIDS-related mortality have dropped by 69% since their peak, with considerable reductions among women and girls, who nevertheless make up 53% of individuals living with HIV. Despite these advancements, difficulties remain. Stigma and unequal access to healthcare remain important impediments, particularly in Eastern Europe, Central Asia, Africa, and the Middle East. In 2023, 630,000 individuals died from AIDS-related illnesses, highlighting the urgent need for comprehensive care and mitigation.

UNAIDS
Strategic priority 1:
Ensuring that everyone has access to HIV services, including key populations at higher risk of HIV, such as sex workers, men who have sex with men, and people who inject drugs.
Strategic priority 2:
Tackling stigma, discrimination, and gender inequality that drive HIV vulnerability, particularly in marginalized populations. Advocating for legal reforms to protect human rights, reduce stigma, and enable equitable access to HIV services.
Strategic priority 3:
Building resilient health systems that can address not only HIV but also other health needs, such as TB and maternal health. Securing sustainable financing for HIV programs, ensuring that funding reaches the most vulnerable and ensures progress towards ending AIDS.

Since its discovery in 1981, the HIV/AIDS epidemic has impacted the history of global health, emphasizing humanity's deficiencies while also demonstrating resilience and ingenuity. What began as a strange ailment mostly affecting young males in the United States quickly turned into a global crisis. In 1983, scientists discovered that the human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS), a condition that annihilates the immune system and renders the body incapable to fight infections.

By the 1990s, AIDS had become one of the most dreadful health catastrophes in modern history, killing millions of people each year. The epidemic's peak in 2004 witnessed almost 2 million deaths in a single year, with marginalized communities—gay males, sex workers, and sub-Saharan African populations—bearing the brunt of the disease's impact. 

During the early decades, the situation was aggravated by global inaction, as well as stigma and prejudice. Treatments were severely limited, and the virus's mysterious nature fuelled fear and misinformation. Despite the despondency, grassroots movements and advocates formed to demand equity, education, and action. These activities paved the way for future advances in HIV/AIDS treatment and prevention.

Today, the HIV/AIDS story is one of progress and opportunity. Antiretroviral therapy (ART) was introduced in the mid-1990s and has become widely available in recent years, allowing people living with HIV to enjoy long, healthy lives. ART works by reducing viral load in the bloodstream to undetectable levels, hence stopping transmission. This notion, represented in the potent U=U (Undetectable = Untransmittable) statement, has formed the foundation of global HIV prevention efforts.

By 2022, roughly 28 million people globally would be receiving ART, demonstrating the collaborative efforts of governments, organizations, and healthcare systems. As a result, annual AIDS-related mortality have dropped by 69% since their peak, with considerable reductions among women and girls, who nevertheless make up 53% of individuals living with HIV. Despite these advancements, difficulties remain. Stigma and unequal access to healthcare remain important impediments, particularly in Eastern Europe, Central Asia, Africa, and the Middle East. In 2023, 630,000 individuals died from AIDS-related illnesses, highlighting the urgent need for comprehensive care and mitigation.

Strategies and Treatments

Kick and Kill
Scientific discoveries are also influencing the course of disease. The 'kick and kill strategy, developed at UCLA, represents novel approaches of eliminating HIV reservoirs in the body. Early animal trials have demonstrated the potential for total viral eradication, providing a glimpse of future without HIV.

Since its discovery in 1981, the HIV/AIDS epidemic has impacted the history of global health, emphasizing humanity's deficiencies while also demonstrating resilience and ingenuity. What began as a strange ailment mostly affecting young males in the United States quickly turned into a global crisis. In 1983, scientists discovered that the human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS), a condition that annihilates the immune system and renders the body incapable to fight infections.

By the 1990s, AIDS had become one of the most dreadful health catastrophes in modern history, killing millions of people each year. The epidemic's peak in 2004 witnessed almost 2 million deaths in a single year, with marginalized communities—gay males, sex workers, and sub-Saharan African populations—bearing the brunt of the disease's impact. 

During the early decades, the situation was aggravated by global inaction, as well as stigma and prejudice. Treatments were severely limited, and the virus's mysterious nature fuelled fear and misinformation. Despite the despondency, grassroots movements and advocates formed to demand equity, education, and action. These activities paved the way for future advances in HIV/AIDS treatment and prevention.

Today, the HIV/AIDS story is one of progress and opportunity. Antiretroviral therapy (ART) was introduced in the mid-1990s and has become widely available in recent years, allowing people living with HIV to enjoy long, healthy lives. ART works by reducing viral load in the bloodstream to undetectable levels, hence stopping transmission. This notion, represented in the potent U=U (Undetectable = Untransmittable) statement, has formed the foundation of global HIV prevention efforts.

By 2022, roughly 28 million people globally would be receiving ART, demonstrating the collaborative efforts of governments, organizations, and healthcare systems. As a result, annual AIDS-related mortality have dropped by 69% since their peak, with considerable reductions among women and girls, who nevertheless make up 53% of individuals living with HIV. Despite these advancements, difficulties remain. Stigma and unequal access to healthcare remain important impediments, particularly in Eastern Europe, Central Asia, Africa, and the Middle East. In 2023, 630,000 individuals died from AIDS-related illnesses, highlighting the urgent need for comprehensive care and mitigation.

The future of HIV/AIDS looks bright, thanks to ambitious goals and ground-breaking research. UNAIDS has set lofty goals for reducing new infections by 75% by 2025 and eliminating AIDS-related deaths by 2030. Efforts to attain these goals are centered on resolving socioeconomic disparities, increasing healthcare access for marginalised groups, and countering stigma through education and awareness campaigns.

Scientific discoveries are also influencing the course of the disease. The "kick-and-kill" strategy, developed at UCLA, represents novel approaches of eliminating HIV reservoirs in the body. Early animal trials have demonstrated the potential for total viral eradication, providing a glimpse of a future without HIV. Injectable ART formulations that require only monthly or biannual dosages hold promise for improving adherence to treatment, while research into broadly neutralizing antibodies (bNAbs) may pave the path for an effective HIV vaccine. Furthermore, attempts to limit mother-to-child transmission have been remarkably successful, with some countries practically eradicating this pathway entirely.

Strategies and Treatments

Kick and Kill
Scientific discoveries are also influencing the course of disease. The 'kick and kill strategy, developed at UCLA, represents novel approaches of eliminating HIV reservoirs in the body. Early animal trials have demonstrated the potential for total viral eradication, providing a glimpse of future without HIV.

ART
ART has been a game-changer, allowing people to live longer, healthier lives.Over 28 million people globally are receiving ART, reducing HIV to undetectable levels, making transmission virtually impossible.While ART access has expanded, millions are still not receiving treatment, especially in regions like Eastern Europe, Central Asia, and the Middle East.

UNAIDS
Strategic priority 1:
Ensuring that everyone has access to HIV services, including key populations at higher risk of HIV, such as sex workers, men who have sex with men, and people who inject drugs.
Strategic priority 2:
Tackling stigma, discrimination, and gender inequality that drive HIV vulnerability, particularly in marginalized populations. Advocating for legal reforms to protect human rights, reduce stigma, and enable equitable access to HIV services.
Strategic priority 3:
Building resilient health systems that can address not only HIV but also other health needs, such as TB and maternal health. Securing sustainable financing for HIV programs, ensuring that funding reaches the most vulnerable and ensures progress towards ending AIDS.

World AIDS Day is a sobering reminder of the path from despair to promise.  It commemorates the lives lost, celebrates the progress made, and renews the world's commitment to ending the pandemic. The fight against HIV/AIDS is far from ended, but the progress accomplished sends a clear message: with inventiveness, compassion, and collaborative effort, an AIDS-free future is possible.